Basic concepts in population, quantitative, and evolutionary genetics Full-Text · PDF Open Access; Can Population Genetics Adapt to Rapid Evolution?. Principles of population genetics (2nd edn). by Daniel L. Hartl and Basic concepts in population, quantitative, and evolutionary genetics. Bear. Cell January Principles of population genetics, 2nd ed. By Daniel L. Hartl and Andrew G. Clark . Sunderland, MA: Sinauer Associates, Inc. xiii + pp., figures, tables.
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PRINCIPLES OF POPULATION GENETICS FOURTH EDITION Daniel L. Hartl Harvard University Andrew G. Clark Cornell University UniversitSts- und Landes- . Principles of Population Genetics. Leo P ten Kate, MD, PhD. Em. Prof. of Clinical Genetics. VU University Medical Center. Amsterdam, the Netherlands. Training. PRINCIPLES OF. POPULATION. GENETICS. FOURTH EDITION. Daniel L. Hartl. Harvard University. Andrew G. Clark. Cornell University. Sinauer Associates.
In the first 3 editions of their text, Hartl and Clark were able to establish their book as not only a useful introduction to a complex and challenging field but also a highly useful reference that deserves a place on the shelf of any biologist. The fourth edition of the book continues this tradition. The book provides an excellent summary of the basics of population genetics. As usually taught, this can be pretty boring stuff. But the authors have read widely and are able to enliven the discussion where it is needed.
Now it is possible to examine norms of reaction at the molecular level. The authors discuss new work by Landry et al.
Gene , in which changes in the transcriptional activity of individual genes in Saccharomyces cerevisiae can be followed as the environment changes. It is now possible to see, using molecular techniques, that the background genotype can have a strong influence on the expression of individual genes and that this influence can be extremely environment dependent.
The text also does not discuss the new and exciting approaches to the process of speciation that are now being made possible by coalescent theory and the availability of entire genomes.
The split between humans and chimpanzees, for example, may be far more complex and lengthy than simple speciation models would predict.
But the book does introduce students to the tools that they can use to probe how speciation takes place.
It is a good place for students to gain an understanding of this fast-moving field. Population genetics is undergoing a revolution, thanks to the availability of vast amounts of comparative sequence data and the invention of new methods by which to examine it.
Each chapter in this revision includes some of this new information. The topic is a vast one, and I am most impressed with how well organized the book is and how much new material has been included in the 10 years since the last revision.
All rights reserved. For permissions, please email: journals. Issue Section:. Various genetic definitions are recalled merely to provide a context for this and more advanced mathematical theory.
Readers with a limited knowledge of modern genetics are urged to learn molecular genetics by formal course work or informal self-study. Appendix A summarizes a few of the major currents in molecular genetics.
In Chapter 15, we resume our study of population genetics from a stochastic perspective by exploiting the machinery of diffusion processes.
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Bennet JH On the theory of random mating. Ann Eugen Freeman, San Francisco Google Scholar. Wiley, New York Google Scholar.